The BIONDD™ technology provides a platform to deliver biologics by the oral route in a standard capsule, by specifically directing the biologic drug molecule inside the stomach wall for safe and effective release to the body. 

With release of the biologic drug molecule inside the stomach wall the usual barriers (degradation and poor absorption from the gut) are circumvented. This results in highly effective oral delivery of the drug equivalent to an injection.


The development of biological pharmaceuticals is growing fast and this has improved the opportunity to treat many serious and widespread diseases. But this type of medication is difficult for the body to absorb. Therefore, to achieve the desired effect, it is necessary to dose much larger amounts of the active substance than is being absorbed by the body. The cost of producing medicine is high and this obviously affects the price. Better utilization of the medicine will therefore mean less wastage and must also be expected to have a positive impact on the price. The alternative may be the use of cumbersome injections, but studies show that over 80% of patients clearly prefer tablets.


Biograil has developed a simple technology consisting of a capsule that opens in the stomach and releases a small hook (of biodegradable PLA) containing the active substances. It briefly attaches itself to the stomach wall and releases the active substances that advance into the bloodstream. The contents of the capsule are soluble and are excreted naturally. It gives the same high power as using injections, while avoiding the disadvantages. It can furthermore reduce the high costs and waste of resources in the production of medicine.

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Introduction to Biograil

BIONDD Technology.

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